Staphyloccal Scalded Skin Syndrome in mouse

Photo: SSSS in ddY mouse. Upper 2 mouses were subcutaneously injected
---------with different doses of the Staphylococcus aureus which were cultured 
---------from the SSSS patient. Lower one was the control(St. aureus, Cowan I )

----------(provided by Dr Hisanori Konishi, Department of Bacteriology, 
-----------Yamaguchi University School of Medicine)

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Staphylococcal scalded skin syndrome in mouse

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The disease is caused by strains of Staphylococcal aureus, which

produce exofoliative toxins(A or B), which absorbed, cause the

separation of cells within epidermis.

The Staphylococcal aureus, which isolated from the baby with

this disease, was cultured and then Mouse(ddY) was inoculated

subcutaneously with the its Staphylococci. A positive Nikolsky

sign(peeling of skin) indicate the epidermolytic activity or

presence of exfoliative toxins.

Any questions: write to Keiji Hagiwara, MD

------------------------------  keijihagiwara@gmail.com