MMR vaccine in Japan

Photo:  MMR vaccine( Measles-Mumps-Rubella combined) 

              stopped in April 1993 in Japan, since aseptic meningitis

               occurred among child who received this vaccine at a

               rate of 1/300~1/1200. At present, not available in Japan)

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MMR vaccine  and aseptic meningitis

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In April 1989, MMR(Measles-Mumps-Rubella) vaccine was 

introduced in Japan. and then its side effect were reported

more frequently year after year.  

The vaccine strains of Mumps viruses(Urabe Am9 strain)

caused meningitis.  In April 1993, Ministry of Health & Welfare 

decided to stop this vaccine. 

   The frequency of aseptic meningitis among child who

          received MMR vaccine in Yamaguchi prefecture.

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       1989                  11/13,269            ( 1/1,206)

       1990                  14/ 7,510             ( 1/  578)

       1991                    8/ 5,728             ( 1/ 716)

       1992                   6/ 4,512              ( 1/ 752)

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At present, Measles-Rubella vaccine administer at age 

1 year, and second dose of  age at 5-7 years.

Any questions:   write to Keiji Hagiwara, MD
--------------------------------Kami-Ube Pediatric Clinic,
--------------------------------1-20-2 Tokiwadai, Ube 755-0097, Japan
-------------------------------- keijihagiwara@gmail.com