22 November, 2009

Automatic blood cell counter

I purchase the new automatic blood cell counter. because the breakdown
of the former machine, which worked for 12 years.

--------------------------------LC-660(not sold in USA), HORIBA, Ltd.
                        → http://www.horiba.com/us/en/
Using 10 micro-litter whole blood, you can measure WBC, RBC,
Hgb,HcT, Platelet and the percentages of lymphocyte, monocyte,
and granulocyte. it take only one minute.

Any questions: write to keijihagiwara@gmail.com

21 November, 2009

Roseola(= Exanthema subitum)

Roseola(= Exanthema subitum)

【Case 1. One-year-old baby】
||||||||||||||||||||||||||||The body temperature in this case is not so high.

||||||||||||||||Usually, the rash of Roseola is unclear one. This case is relatively
||||||||||||||||clear cut one, look like the initial stage of " Measles" rash.
||||||||||||||||The low resolution of Blog's Photography is not suitable to show
||||||||||||||||skin eruption.

【Case 2.  9-month-old boy】
||||||||||||||||||||||A fever chart: good record !
||||||||||||||||||||||His mother described that skin eruption appear from
||||||||||||||||||||||abdomen→ back|→ face→ hand & foot.

Roseola(= Exanthema subitum)
◎Ages: 6-month-old ~ 1.5-year-old
◎Etiology: human herpes virus 6, and 7(rare) and less frequently 
Electron-microscopy of HHV-6(x 25,000), Dr. Kazuto Yamaguchi,
Department of Animal Experiment, Yamaguchi University School of Medicine.

◎Ethinic: Roseola is very common in Japanese infant, 2/3 infants suffer
|||||||||||||from this condition. Asian infants (Chinese, Korean ) may suffer
|||||||||||||similar frequency.
◎Clinical course:
|||||||||||||||||1) High fever(39~40℃) last for 3~5 days. but infant do not
||||||||||||||||||||seem very sick.
|||||||||||||||||2) no cough, no runny nose( frequently, loose or watery stool) .
|||||||||||||||||3) a fever subside, then a red rash appear in body.
||||||||||||||||||||The type of rash is variable; Rubella like, Measles like, or
||||||||||||||||||||diffuse pink rash. Rash disappear in several days.
➞    The skin eruption of Roseola is unclear one and many different types.
|||||||||||Sometimes mother will not notice ----- so carefully observe the baby
|||||||||||skin. This is one reason why Roseola's frequency is different among ethnic
|||||||||||groups or nations.

|||||||||||||||1) febrile convulsion
|||||||||||||||2) encephalitis (rare)

Any questions : write to 

-------- Keiji Hagiwara, MD
-------- Kami-Ube Pediatric Clinic
-------- Ube 755-0097, Japan
-------- keijihagiwara@gmail.com

19 November, 2009

Starting the Swine N1H1 vaccine for child

Photo ---------- Two type of Swine flu vaccine(10ml vial and 1.0ml vial)
, made by KAKETSUKEN, The chemo-Sero-Therapeutic Research Institute,

Today(November 21th, 2009), I start to shot the Swine flu vaccine for 41 child
with two groups;
------ i) The child with underlying disease(Bronchial asthma et ct.)
------ ii)1~ 5 year old with "normal child".

The distribution of Swine flu vaccine to Hospitals and Clinics is too slow in
Japan. On 16th November, I had received 10 vials(one bottle contain 10ml)
of the Swine flu(A,N1H1) vaccine from local health authority of Yamaguchi

※The charge of vaccine(National-wide rates): first (3,600 yen), second (2,550 yen)

Age ----------------------------The dosage of vaccine
1~ 5 -year- old---------------0.2ml x 2 times (apart 1~4 weeks)
6~12 -year-old---------------0.3ml x 2 times (apart 1~4 weeks)
13 year old > ----------------0.5ml x 2 times (apart 1~4 weeks)

If you wish to be vaccination for your child(1~5 year old only),
please call to reservation (Tel : 0836-29-1155).

Thank you,

Keiji Hagiwara, MD
Kami-Ube Pediatric Clinic,
1-20-2 Tokiwadai, Ube 755-0097
Tel: 0836-29-1155

E-mai: 1) keijihagiwara@gmail.com
2) keiji-hagiwara@umin.ac.jp

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08 November, 2009

Sweet potato

Today, I harvest the sweet potatoes (a variety name:鳴門金時)
in my small garden. You may need to dig deeper around 1 m.
I miss to cut some of them with hoe.

03 November, 2009

Tamiflu and a chinese herb(八角)

Chinese star anise fruits (Chinese: 八角, pinyin: bājiǎo ) is the traditional herb
of the Chinese cooking.

It is the starting material of anti-influenza virus drug Oseltamivir (trade name=

The shikimic acid is extracted from the seeds of star anise in a ten-stage process.
Then, Tamiflu is chemically synthesized(at least 14 steps are necessary) from it.

Thirteen grams of star anise make 1.3 grams of shikimic acid, which can be
made into 10 capsules(oseltamivir 75 mg/ capsule, for treatment of one Pearson).

Star anise is grown in four provinces in China and harvested between March
and May. It is also produced in Lang Son province, Vietnam.

Any questions: write to keijihagiwara@gmail.com

Swine flu( 12-year-old)

Two records of 12-year-old boy with Swine flu, who were treated with Relenza.
In these cases, excellent effect of Relenza.

Relenza is a type of oral inhalation drug for influenza A, B, or swine H1N1influenza

Any questions: write to keijihagiwara@gmail.com
Cover your nose with a tissue when you sneeze. Visit www.flu.gov for more information.

Swine flu( 6-year-old)

October 25th. At evening, started fever.
|||||||| ------ Rapid test: influenza-A(+).
|||||||| ------ prescribed Tamiflu dry syrup & acetaminophen granules.
||||||| ---------------- A record of body temperature: 6-year-old. Arrow indicate Tamiflu
||||||| dry syrup intake.

Any questions: keijihagiwara@gmail.com

Show your child how to wash his hands. Visit www.flu.gov for more information.

Swine flu (2-year-old)

Last week, The Swine flu have been spreading among the elementary school
children in Ube(宇部). It's late start, since Ube city is situated far from the
big city, such as Fukuoka(福岡) or Hiroshima(広島).
October 27th. 2-year-old. mother noticed fever at mid-night.
||||| ------- 28th. came to my clinic.
||||| -------------- Rapid test : influenza-A(+)
||||| -------------- prescribed Tamiflu dry syrup, cough syrup & acetaminophen.

|||||||| --------------- Tamiflu dry syrup( a powder for oral suspension )

||||||||| ---------------- arrow indicate Tamiflu intake.

Any questions: write to keijihagiwara@gmail.com