25 July, 2008


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|||||||||||||||||||||||||||||||||||A party at ICP, UCL, Brussels Belgium in 1985.
||||||||||||||||||||||||||||||||||Lab. members at MEXP, ICP, UCL Brussels. 1985.
|||||||||||||||||||||||||||||||||||King Boudouin of Belgium visited the MEXP, Christian de
|||||||||||||||||||||||||||||||||||Duve Institute of Cellular Pathology,UCL, Brussels.
|||||||||||||||||||||||||||||||||||Professor Masson made a mini-lecture in the front of the particle
|||||||||||||||||||||||||||||||||||counting immunoassay apparatus in October 1985.

|||||||||||||||||||||||||||||||Princess Fabiola of Belgium visited Christian de Duve Institute of
|||||||||||||||||||||||||||||||Cellular Pathology in October 1985.
||||||||||||||||||||||Right; Dr. de Duve (Nobel Laureate in Physiology or Medicine in 1974).

Those are old photos. In the beginning of October 1985, King Boudouin and
Princess Fabiola visited the medical research center, named " Christian de
Duve Institute of Cellular Pathology ", Universite Catholique de Louvain,
Brussels, Belgium, where I had been working as a guest investigator.

King Bouduin made a short stop in the front of me, and
||||||||||||||||||||||||||||||||said ------ " Are you come from Japan ? "
|||||||||||||||||||||||||||||||||||||||||------ " Yes, Ube city, Yamaguchi, Japan.
||||||||||||||||||||||||||||||||||||||||||||||||||||||||Yamaguchi University School of Medicine "

Then, I followed the King with my camera and looked round the institute.
It's lucky chance to take the photo of King Bouduin. The Belgian are polite.
Nobody took photographs. However, afterward , many requests of photo's
reprints came upon me from the members of Catholic University of Louvain.

I studied a sugar-binding protein(lectin) Jacalin. Jacalin bind to
human immunoglobulin A1 molecule, but not bind to immunoglobulin A2,
immunoglobulin G, M, D, and E. Jacalin specifically bind to beta 1-3 Gal-GalNac.
and human IgA1 contain its carbohydrate. Nowaday, Jacalin is available from
commercial compamy such as Sigma-Aldrich.

1) Hagiwara K, Collet-Cassart D, Vaerman J-P, Masson PL,: Application of
||||||the quantitative latex agglutination assay to study glycoprotein- lectin
||||||interaction. In, Lectins: Biology, Biochemistry, Clinical Biochemistry.
||||||Vol 6: 505- 511. Sigma Chem. Co., St Louis, Missouri, U.S.A.1988.
2) Hagiwara K, Collet-Cassart D, Kobayashi K, Vaerman J-P; Jacalin:
||||||isolation, characterization and influence of various factors on its interaction
||||||with human IgA1, as assessed by precipitation and latex agglutination.

Any questions: write to Keiji Hagiwara MD,
|||||||||||||||||||||||||||||||||||||||||||||||||||E-mail: keijihagiwara@gmail.com