![](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjjYUJxZdfkUFvPnIMjT4rUXPb0q09EL76SlrO5HEOBx-kBj6ksKSb45TtMGW0cPVQVyb5_nRif2LbobJYWe9mV4dS9lGAi7iQ4Ao5yJOsheHbG1uUs_3WiWImc7geTJDnREQmRMx9jvMOC/s400/%E6%89%8B%E8%B6%B3%E5%8F%A3%E7%97%85%EF%BC%88%E5%8F%A3%EF%BC%89.jpg)
![](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEirkGDgx_OI2na2F-9TF-KGoHxSbhSqnyTDjlQekPOvrdD4bkF2EGQu_ylHrKeWE0Nq5jOcLzknZPx1XOuj-uQ8RUMQlqD5cwHA1hZvpHRIhYETA29cCLepg9KisTyCcdstLAB-sFanSb8c/s400/Enterovirus.jpg)
2) Electron-Microscopy of Enterovirus.
------- Dr. Linda Stannard, Department of Medical Microbiology,
University of Cape Towan.
![](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiQLjIq72JF3K6a5BqE6mkuCL_fn2haA8dJOZekwc_rLcVYzXkhLCnmUIEZMx5AiQu22nOklYttGQUAE77agHO50_LiMcljOBAifbPfEKHCMBFDxAOmgEYj_z08RyBvIpT9-OxuJwzaQ-S5/s400/%E6%89%8B%E8%B6%B3%E5%8F%A3%E7%97%85%EF%BC%88%E6%89%8B%EF%BC%89.jpg)
3) small vesicles in hand
4) Knee region
5) small vesicles in hip
![](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEh4mRSKtESn5ISIIneS6fuiDeZzCA0KOLd0EXfF2E47pNjDWBQTBT2mGXaqSe7t4p1K7QCky1X6k5Q4cbyAO-orUbDksKDxPP20jinPKKw2PjMhiR9Y1m1bXV67JmHfdwdgxApRLUckLj8d/s400/%E6%89%8B%E8%B6%B3%E5%8F%A3%E7%97%85%EF%BC%88%E8%86%9D%EF%BC%89.jpg)
![](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgEJLRPoIKGAKPttvZn8K6CcJTbigjHxb30j1Pdw6dnxxYwqJJTlidEbBPMEQ61bqwzYtimikXFonqTYdSE2vhFXYSmqICfnkEGDLMIOhmmdA2jAKB4GXMGLTO_RQzykxype68gJbuDKFUC/s400/%E6%89%8B%E8%B6%B3%E5%8F%A3%E7%97%85%EF%BC%88%E3%81%8A%E5%B0%BB%EF%BC%89.jpg)
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Hand-Foot-Mouth disease
❑ Symptoms: small vesicles(no itching) appeared in oral,
hand, foot, knee and hip
❑ Etiology: Coxsackie viruses , enteroviruses
❑ Epidemiology: epidemic in summer among children
❑ Age: infant, toddlers, primary school child
❑ Incubation period: 3-6 days
❑ Route of transmission: oral-fecal,
❑ Natural course: resolved in 1 week
Cautions: Hand-Foot-Mouth disease is benign disease,
but in the cases due to Enterovirus 71, Central
nerves system infection such as meningo-encephalitis
and Polio-like illness occur in child.
see also → http://en.wikipedia.org/wiki/Hand,_foot_and_mouth_disease
Any Questions: write to
Keiji Hagiwara, MD
Kami-Ube Pediatric Clinic,
E-mail: keijihagiwara@gmail.com