12 March, 2009

Herpangina

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Herpangina
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1) Season: Summer
2) Age: infant and toddlers
3) Course of illness:
fever and throat pain resolved few days or more longer.

Photo) Throat of Herpangina. Small vesicles appear in palate.


4) Etiology: Enterovirus

Photo) Electron-Micrograph of Enterovirus
------ Dr.Linda Stannard, University of Cape Town.



Any questions: write to Keiji Hagiwara, MD
keijihagiwara@gmail.com

11 March, 2009

Adenovirus infection in child (1-year-old & 6-year-old)

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Adenovirus infection in child(2)
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---------------- 1 year & 10 month-old girl:
|||||||||| April 5th 2004. fever & cough at morning.
|||||||||| 6th. came to Clinic. reddish white coated tonsil(+).
|||||||||| Rapid test for adenovirus(+).
|||||||||| 9th. fever fell down.


----------------- 6 year old girl (same patient as above).
|||||||||||||| But this time no so severe ----- may due to some immunity to adenovirus

|||||||||||||| March 4th, 2009. high fever & throat pain at evening. no cough.
|||||||||||||| Tonsil: red(+) pus(-).
|||||||||||||| adenovirus test (+).
|||||||||||||| March 7th. fever fell down.

1) Adenovirus: DNA virus. 47 serotype

-------- Dr. Linda Stannard, Department of Microbiology, University of Cape Town.


2) Season: winter ~ spring ~ early summer.
3) Age: 6 month old~ toddlers.
4) Transmission route: child to child.
||||||| close contact through droplets.
||||||| feces~oral route.
||||||| ------- Child with adenovirus infection have excreted its viruses in feces
|||||||-------  for long period( 2 weeks).

5) main site of infection: kindergarten.
6) incubation period: 2~14 days.
7) Type of diseases:
||||||| So many types of adenovirus have been circulating,

||||||| child may be 2, 3 or more times suffered from this virus.
||||||| But don't worry,your child gradually immune to this virus.

||||||| i) Pharingitis, Tonsillitis: common

||||||| ii) Acute bronchitis & pneumonia: infant, at risk in premature born baby.
||||||| iii) conjunctivitis & keratitis: common in summer.

||||||| iv) Acute gastroenteritis: serotypes 31, 40, 41.

||||||| v) Hemorrhagic cystitis: toddler ~ 10 year old.
||||||| vi) Pertussis(whooping cough ) like illness: rare.


Any questions: write to Keiji Hagiwara MD,
keijihagiwara@gmail.com

RS virus infection( 1-year & 7-month-old)


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RS virus infection in infant
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||||||||||||||| ☞ Case presentation:
|||||||||||||||| ------- 1 year 7 month-old boy (acute wheezing bronchitis).
||||||||||||| January 19th. started high fever & cough.
|||||||||||||||||||||||||||| 20th. severe cough with wheezing at night.
||||||||||||||||||||||||||||||||||||||| Rapid diagnostic test for RS virus(+).
|||||||||||||||| 25th. no fever. cough & wheezing continued.
|||||||||||||||| February 2th. still coughing.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Respiratory Syncytial(=RS) virus: RNA virus
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
------------ Linda Stannard, Department of Medical Microbiology, University of Cape Town.

2) Age: 6 month old ~ toddlers
3) Season: winter~ early spring.
4) Incubation period: 2~8 days
5) Transmission route: close contact with infected infants.
|||||||||||||||||||||||||||||||||||||||||||||droplets, aerosol inhalation.

6) Site of infections: kindergarten, child care centers
7) Type of diseases:
||||||||||||||| i) upper respiratory infection: frequent
|||||||||||||| ii) wheezing bronchitis: infants
||||||||||||| iii) Acute bronchiolitis: apnea(holding respiration)
||||||||||||| iv) pneumonia:
8) Prevention: monoclonal antibody to RS virus(Trade name SYNAGIS)
------------------ , its high costs, is administered in one shot/month during winter
-------------------- for high risk baby  ☞ low-birth-weight infant, premature baby 
==============================or infant with congenital heart diseases.




Any questions: write to Keiji Hagiwara MD. keijihagiwara@gmail.com